If you use Firefox, you'll love the Firefox add-on DragDropUpload. You can literally drag files from your desktop into the attachment field of ReplyManager instead of clicking on the Browse button to upload the file from your computer.
To start using it, download the application from Firefox at https://addons.mozilla.org/en-US/firefox/addon/2190 and install. If you don't already have the latest and greatest version of Firefox, you'll need to update that too. This application works best with Firefox 3.